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Your Position: 홈 > Protein > LAG-3 > LA3-C52H7

Canine LAG-3 / CD223 Protein, His Tag (MALS verified)

소개
QC & ASSAY PROTOCOL
CITATION & BACKGROUND
  • 동의어
    LAG3,CD223,FDC
  • 출처
    Canine LAG-3, His Tag (LA3-C52H7) is expressed from human 293 cells (HEK293). It contains AA Pro 23 - Leu 440 (Accession # XP_038295087.1).
    Predicted N-terminus: Pro 23
    Request for sequence
  • 분자 표징
    Online(Pro 23 - Leu 440) XP_038295087.1

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 46.8 kDa. The protein migrates as 55-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • 내독소
    Less than 1.0 EU per μg by the LAL method.
  • 순도

    >95% as determined by SDS-PAGE.

    >90% as determined by SEC-MALS.

  • 레시피

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

    Contact us for customized product form or formulation.

  • 재구성

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • 보관

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
Canine LAG-3, His Tag (Cat. No. LA3-C52H7) SDS-PAGE gel

Canine LAG-3, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.

SEC-MALS
Canine LAG-3, His Tag (Cat. No. ) MALS images

The purity of Canine LAG-3, His Tag (Cat. No. LA3-C52H7) is more than 90% and the molecular weight of this protein is around 96-116 kDa verified by SEC-MALS.

Report
  • 백그라운드
    Lymphocyte activation gene 3 protein (LAG3) is also known as CD antigen CD223 and protein FDC, which belongs to immunoglobulin (Ig) superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4. LAG3 /CD223 involved in lymphocyte activation. LAG3 /CD223 binds to HLA class-II antigens.
  • Clinical and Translational Updates
      

  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

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