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Your Position: > Protein > CD84 > CD4-H5229

Human CD84 / SLAMF5 Protein, His Tag

  • Synonym
    CD84,SLAMF5,LY9B,SLAMF5
  • Source
    Human CD84, His Tag(CD4-H5229) is expressed from human 293 cells (HEK293). It contains AA Lys 22 - Gly 225 (Accession # AAH20063).
    Predicted N-terminus: Lys 22
  • Molecular Characterization
    CD84 Structure

    This protein carries a polyhistidine tag at the C-terminus

    The protein has a calculated MW of 23.6 kDa. The protein migrates as 38-50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Purity

    >95% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
CD84 SDS-PAGE

Human CD84, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.

  • Background
    Leukocyte differentiation antigen CD84 is also known as SLAM family member 5 (SLAMF5), which belongs to immunoglobulin (Ig) superfamily. CD84 / SLAMF5 contains one Ig-like C2-type (immunoglobulin-like) domain. CD84 plays a role as adhesion receptor functioning by homophilic interactions and by clustering. CD84 / SLAMF5 increases proliferative responses of activated T-cells and SH2D1A/SAP does not seen be required for this process. Homophilic interactions enhance interferon gamma/IFNG secretion in lymphocytes and induce platelet stimulation via a SH2D1A/SAP-dependent pathway.
  • Clinical and Translational Updates

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재고상품 출발날짜: 영업일 기준 4일

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Datasheet & Documentation

DMF 신청
DMF (Drug Master File)

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