로그인 회원가입
icon_bulk_order대량 주문 Acrobiosystems for English
Promotion
Recombinant Proteins ClearClear history
Recombinant Proteins CloseClose
Browse Products By Molecule Name a-zA-Z
TL1A Hot |GMP IL-2 Hot |FcRn Binding Kit (TR-FRET) New |Claudin 18.2 Hot
0
장바구니가 비어 있습니다
내 장바구니
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 0-9
Your Position: 홈 > Protein > IL-3 R alpha > ILA-HA2H8

APC-Labeled Human IL-3 R alpha / CD123 Protein, His Tag (Site-specific conjugation)

INTRODUCTION
QC & Assay Protocol
Citation & Background
  • Synonym
    IL3R,IL3RA,IL-3Ra,IL-3R-alpha,IL3RAY,IL3RX,IL3RY,CD123 antigen,CD123,hIL3Ra,hIL-3Ra,MGC34174,IL-3 R alpha
  • Source
    APC-Labeled Human IL-3 R alpha Protein, His Tag (ILA-HA2H8) is produced via conjugation of APC to Human IL-3 R alpha Protein, His Tag with a new generation site-specific technology under optimal conditions with a proprietary technology. Human IL-3 R alpha Protein, His Tag is expressed from human 293 cells (HEK293). It contains AA Thr 19 - Arg 305 (Accession # P26951-1).
    Predicted N-terminus: Thr 19
    Request for sequence
  • Molecular Characterization
    IL-3 R alpha Structure

    This protein carries a polyhistidine tag at the C-terminus

    The protein has a calculated MW of 36.7 kDa.

  • Conjugate

    APC

    Excitation Wavelength: 640 nm

    Emission Wavelength: 661 nm

  • Application
    Please note that this product is NOT compatible to streptavidin detection system.
  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, 0.5% BSA, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please protect from light and avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
Bioactivity-FACS
IL-3 R alpha FACS

5e5 of anti-IL-3 R alpha CAR-293 cells were stained with 100 μL of 1:25 dilution (4 μL stock solution in 100 μL FACS buffer) of APC-Labeled Human IL-3 R alpha Protein, His Tag (Cat. No. ILA-HA2H8) and negative control protein respectively. APC signal was used to evaluate the binding activity (QC tested).

Protocol
  • Background
    Interleukin 3 receptor alpha (low affinity) (IL3RA), also known as CD123 (Cluster of Differentiation 123) is a 70-kD glycoprotein member of the hematopoietin receptor superfamily. This protein associates with a beta subunit common to the receptors for IL-5 and granulocyte-macrophage colony-stimulating factor (GM-CSF) to form a high-affinity receptor for IL-3. The interleukin-3 receptor α chain (CD123) has been identified as a potential immunotherapeutic target because it is overexpressed in AML compared with normal hematopoietic stem cells.
  • Clinical and Translational Updates

코멘트 (0)


재고상품 출발날짜: 영업일 기준 4일

가격(KRW) : 502,500

가격(KRW) : 3,120,000

장바구니에 담기 대량구매 맞춤형 제품

Antibody Licensing

more

보급 및 전시



약물 개발 현황

  • Number of Launched Drugs：1 Details
  • Number of Drugs in Clinical Trials：36 Details
  • Latest Research Phase：Approved
다른 추천 제품

Datasheet & Documentation

DMF 신청
DMF (Drug Master File)

연락처

+1  800-810-0816 (US)
+86 400-682-2521 (AP)
Show All Distributors

관련 제품

신제품

문의와 컨텐츠

This web search service is supported by Google Inc.

totop
Call us
우리에게 전화하세요
글로벌: +1 800-810-0816 (무료)
아시아태평양: +86 400-682-2521
Email
이메일
order.kr@acrobiosystems.com
Fax
팩스
+1 888-377-6111
Address
주소
서울 성동구 왕십리로10길 6 서울숲비즈포레 703
회사명
아크로바이오 주식회사
사업자 등록번호
186-88-02858
대표자
CHEN YIDING
사업장주소
서울특별시 송파구 중대로12길 10-20, 1층 셀렉티드송파(가락동)
linkedin twitter facebook youtube

문의

Copyright © 2017 ACROBiosystems. All Rights Reserved
Related Links|Privacy Policy|Terms and Conditions|Legal|Sitemap