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Your Position: > Protein > ALPP > ALP-H52H3

Human ALPP Protein, His Tag (MALS verified)

  • Synonym
    PLAP
  • Source
    Human ALPP Protein, His Tag(ALP-H52H3) is expressed from human 293 cells (HEK293). It contains AA Ile 23 - Asp 506 (Accession # P05187-1).
    Predicted N-terminus: Ile 23
  • Molecular Characterization
    ALPP Structure

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 54.7 kDa. The protein migrates as 64-66 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Purity

    >90% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in 20 mM Tris,150 mM NaCl,pH7.5 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
ALPP SDS-PAGE

Human ALPP Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).

SEC-MALS
ALPP MALS images

The purity of Human ALPP Protein, His Tag (Cat. No. ALP-H52H3) is more than 85% and the molecular weight of this protein is around 105-135 kDa verified by SEC-MALS.

Bioactivity-ELISA
 ALPP ELISA

Immobilized Human ALPP Protein, His Tag (Cat. No. ALP-H52H3) at 1 μg/mL (100 μL/well) can bind various dilution ratio of Anti-ALPP/ALPG/ALPI Polyclonal Antibody (QC tested).

  • Background
    ALPP is highly expressed in a variety of solid tumors, including ovarian, endometrial, germ cell, non-small cell lung, bladder and gastric cancers.In normal tissues, it is expressed in the placenta and low in lung and reproductive tissues.ALPP is a membrane protein and exits as a homodimer.
  • Clinical and Translational Updates

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재고상품 출발날짜: 영업일 기준 4일

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  • Latest Research Phase:Phase 2 Clinical

Datasheet & Documentation

DMF 신청
DMF (Drug Master File)

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