Limited Edition Golden Llama is here! Check out how you can get one. 
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Offering SPR-BLI Services - Proteins provided for free! Offering SPR-BLI Services - Proteins provided for free!
Here come GMP Grade Cytokines！Free Sample is available！ Here come GMP Grade Cytokines！Free Sample is available！
5e5 of anti-IL-3 R alpha CAR-293 cells were stained with 100 μL of 1:25 dilution (4 μL stock solution in 100 μL FACS buffer) of APC-Labeled Human IL-3 R alpha Protein, His Tag (Cat. No. ILA-HA2H8) and negative control protein respectively. APC signal was used to evaluate the binding activity (QC tested).
5e5 of anti-IL-3 R alpha CAR-293 cells were stained with 100 μL of 1:25 dilution (4 μL stock solution in 100 μL FACS buffer) of PE-Labeled Human IL-3 R alpha, His Tag (Cat. No. ILA-HP2H8) and negative control protein respectively. PE signal was used to evaluate the binding activity (QC tested).
Anti-IL-3 R alpha Antibody, Human IgG1 immobilized on CM5 Chip can bind Human IL-3 R alpha, Fc Tag (Cat. No. ILA-H5252) with an affinity constant of 50.3 nM as determined in a SPR assay (Biacore T200) (QC tested).
| Name | Research Code | Research Phase | Company | First Brand Name | First Approved Country | First Indication | First Approved Company | First Approved Date | Indications | Clinical Trials |
|---|---|---|---|---|---|---|---|---|---|---|
| Tagraxofusp | DTIL-3; DT388 IL3; SL-401 | Approved | Texas A&M University Development Foundation | Elzonris | EU | Lymphoma; Blastic Plasmacytoid Dendritic Cell Neoplasm | Stemline Therapeutics Inc | 2018-12-21 | Leukemia; Leukemia, Myelomonocytic, Chronic; Myelodysplastic Syndromes; Blastic Plasmacytoid Dendritic Cell Neoplasm; Multiple Myeloma; Primary Myelofibrosis; Leukemia, Myeloid, Acute; Lymphoma | Details |
| Name | Research Code | Research Phase | Company | Indications | Clinical Trials |
|---|---|---|---|---|---|
| Anti-CD123 CAR T-cell therapy (Southwest Hospital) | Phase 2 Clinical | Southwest Hospital Chongqing | Leukemia, Myeloid | Details | |
| Anti-CD123 CAR T-cell therapy (Nanjing Legend Biotech) | Phase 1 Clinical | Leukemia, Myeloid, Acute | Details | ||
| Anti-CD123 CAR T cell therapy (Shanghai GeneChem) | Phase 1 Clinical | Shanghai Genechem Co Ltd | Leukemia, Myeloid, Acute | Details | |
| SQZ-622(Novartis Pharma) | SQZ-622 | Phase 1 Clinical | Novartis Pharma Ag | Leukemia, Myeloid, Acute | Details |
| Anti-CD123 CAR T-cell therapy (University of Pennsylvania/Novartis) | JEZ-567 | Phase 1 Clinical | Novartis Pharma Ag, University Of Pennsylvania | Leukemia, Myeloid, Acute | Details |
| UniCAR02-T | UniCAR02-T | Phase 1 Clinical | Cellex Patient Treatment Gmbh | Kidney Neoplasms; Prostatic Neoplasms; Breast Neoplasms; Colorectal Neoplasms; Carcinoma, Non-Small-Cell Lung | Details |
| CD123 CAR-T cells (Hebei Senlang Biotechnology) | Hebei Senlang Biological Technology Co Ltd | Details | |||
| CD123 CAR-T cell therapy(Chongqing Precision Biotechnology) | Chongqing Precision Biotechnology Co Ltd | Details | |||
| CD123/CLL1 CAR-T Cell Therapy (Fujian Medical University) | Fujian Medical University | Details | |||
| IM-23 (Beijing Immunochina Medical Science and Technology) | IM-23; IM-23 CAR-T | Beijing Immunochina Medical Science & Technology Co Ltd | Details | ||
| SGN-CD123A | SGN-CD123A | Seattle Genetics Inc | Details | ||
| CSL-360 | IL-3Rα; CSL-360 | Csl Ltd | Details | ||
| UniCAR-T-CD-123 | UniCAR-T-CD123 | Phase 1 Clinical | Gemoab Monoclonals Gmbh | Leukemia, Myeloid, Acute | Details |
| Talacotuzumab | CSL-362; JNJ-473; CSL-362-AML; JNJ-56022473; IL-13 MAb-CSL | Phase 2 Clinical | Csl Ltd | Myelodysplastic Syndromes; Leukemia, Myeloid, Acute | Details |
| JNJ-63709178 | JNJ-9178; CNTO-9958; JNJ-63709178 | Phase 1 Clinical | Janssen Global Services Llc, Genmab A/S | Leukemia, Myeloid, Acute | Details |
| UCART-123 | UCART-123 | Phase 1 Clinical | Cellectis Sa | Blastic Plasmacytoid Dendritic Cell Neoplasm; Leukemia, Myeloid, Acute | Details |
| CD19-CD123 cCAR T-cells Therapy(iCell Gene Therapeutics) | ICG140 | iCell Gene Therapeutics LLC | Details | ||
| MB-102 (Mustang Bio) | MB-102 | Phase 3 Clinical | Mustang Bio Inc, City Of Hope National Medical Center | Neoplasm, Residual; Acute Kidney Injury; Blastic Plasmacytoid Dendritic Cell Neoplasm; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Leukemia, Myeloid, Acute; Leukemia, Biphenotypic, Acute | Details |
| ACLX-002 | ACLX-002 | Phase 1 Clinical | Arcellx Inc | Myelodysplastic Syndromes; Leukemia, Myeloid, Acute | Details |
| Anti-CD123 CAR-T cell therapy (Wuhan Union Hospital) | Phase 1 Clinical | Wuhan Bio-Raid Biotechnology, Wuhan Union Hospital | Leukemia, Myeloid, Acute | Details | |
| Pivekimab sunirine | IMGN-632 | Phase 2 Clinical | Immunogen Inc | Myeloproliferative Disorders; Blastic Plasmacytoid Dendritic Cell Neoplasm; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Leukemia, Myeloid, Acute | Details |
| Vibecotamab | XmAb-14045 | Phase 1 Clinical | Xencor Inc | Leukemia, Myeloid; Blastic Plasmacytoid Dendritic Cell Neoplasm; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Leukemia, Myeloid, Acute | Details |
| Allogenic CD123-CAR-NK Cells therapy(JD Biotech) | JD023 | Phase 1 Clinical | Beijing JD Biotech Co Ltd, Chinese Academy Of Military Medical Sciences | Leukemia, Myeloid, Acute | Details |
| GR-1901 | GR1901; GR-1901 | Phase 1 Clinical | Chongqing Zhixiang Jintai Biopharmaceutical Co Ltd, Zhixiang (Shanghai) Pharmaceutical Technology Co Ltd | Leukemia, Myeloid, Acute | Details |
| APVO436 | APVO-436 | Phase 1 Clinical | Aptevo | Myeloproliferative Disorders; Leukemia, Myeloid, Acute | Details |
| MGD-024 | MGD-024 | Phase 1 Clinical | Macrogenics Inc | Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Hairy Cell; Neoplasms; Hodgkin Disease; Myelodysplastic Syndromes; Blastic Plasmacytoid Dendritic Cell Neoplasm; Leukemia, B-Cell; Leukemia, Myeloid, Acute | Details |
| Flotetuzumab | S-80880; MGD-006; RES-234 | Phase 2 Clinical | Macrogenics Inc | Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Hematologic Neoplasms; Leukemia, Hairy Cell; Hodgkin Disease; Mastocytosis, Systemic; Blastic Plasmacytoid Dendritic Cell Neoplasm; Neoplasms, Plasma Cell; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Leukemia, B-Cell; Leukemia, Myeloid, Acute; Leukemia, Biphenotypic, Acute | Details |
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