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IDH1

요약

Name:Isocitrate dehydrogenase [NADP] cytoplasmic
Target Synonym:IDH,EC 1.1.1.42,PICD,IDCD,Isocitrate Dehydrogenase (NADP(+)) 1,Isocitrate Dehydrogenase 1 (NADP+), Soluble,HEL-S-26,IDH1,Isocitrate Dehydrogenase (NADP(+)) 1, Cytosolic,HEL-216,NADP(+)-Specific ICDH,Cytosolic NADP-Isocitrate Dehydrogenase,IDP,NADP-Dependent Isocitrate Dehydrogenase, Cytosolic,Oxalosuccinate Decarboxylase,Epididymis Secretory Protein Li 26,Isocitrate Dehydrogenase 1 (NADP+),NADP-Dependent Isocitrate Dehydrogenase, Peroxisomal,IDPC,EC:1.1.1.42,Epididymis Luminal Protein 216,Epidid
Number of Launched Drugs:2
Number of Drugs in Clinical Trials:11
Lastest Research Phase:Approved

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제품번호 제품 설명 구조 순도 특징
ID1-H51H8 Human Human IDH1 (R132C) Protein, His Tag (MALS verified)
ID1-H51H8-structure
ID1-H51H8-sds
ID1-H51H6 Human Human IDH1 Protein, His Tag (active enzyme, MALS verified)
ID1-H51H6-structure
ID1-H51H6-sds

일부의 생물활성 데이터

ID1-H51H8-MALS-HPLC
IDH1 MALS images

The purity of Human IDH1 (R132C), His Tag (Cat. No. ID1-H51H8) is more than 85% and the molecular weight of this protein is around 85-100 kDa verified by SEC-MALS.

ID1-H51H6-MALS-HPLC
IDH1 MALS images

The purity of Human IDH1, His Tag (Cat. No. ID1-H51H6) is more than 85% and the molecular weight of this protein is around 90-100 kDa verified by SEC-MALS.

Synonym Name

IDH1,PICD,IDP

Background

Isocitrate dehydrogenase 1 (IDH1) is also known as Cytosolic NADP-isocitrate dehydrogenase (NADP(+)-specific ICDH), Oxalosuccinate decarboxylase and PICD, which is one of the Isocitrate dehydrogenases that can catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD+ as the electron acceptor and the other NADP+. The cytoplasmic enzyme serves a significant role in cytoplasmic NADPH production.

Clinical and Translational Updates

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