로그인 회원가입
icon_bulk_order대량 주문 Acrobiosystems for English
Promotion
Recombinant Proteins ClearClear history
Recombinant Proteins CloseClose
Browse Products By Molecule Name a-zA-Z
TL1A Hot |GMP IL-2 Hot |FcRn Binding Kit (TR-FRET) New |Claudin 18.2 Hot
0
장바구니가 비어 있습니다
내 장바구니
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 0-9
Your Position: 홈 > FcRn (FCGRT & B2M)

FcRn (FCGRT & B2M)

요약

Name:IgG receptor FcRn large subunit p51
Target Synonym:Alpha-Chain,FcRn,Major Histocompatibility Complex Class I-Like Fc Receptor,Immunoglobulin Receptor, Intestinal, Heavy Chain,Neonatal Fc-Receptor For Ig,FcRn Alpha Chain,FCGRT,IgG Fc fragment receptor transporter alpha chain,Neonatal Fc receptor,Fc Fragment Of IgG Receptor And Transporter,Transmembrane Alpha Chain Of The Neonatal Receptor,Fc Fragment Of IgG, Receptor, Transporter, Alpha,IgG receptor FcRn large subunit p51,Heavy Chain Of The Major Histocompatibility Complex Class I-Like Fc Recepto
Number of Launched Drugs:3
Number of Drugs in Clinical Trials:3
Lastest Research Phase:Approved

제품 리스트 구매

제품> 결과 필터링
제품 상태별:
제품 유형별 :
종별:
태그별:
결합물별:
제품번호 종 제품 설명 구조 순도 특징
FRT-01 Human Human FcRn binding Kit (TR-FRET)
CHEK-ATP132 Human HEK293/FcRn (FCGRT & B2M), GFP Tag Stable Cell Line
FCM-H5283 Human Human FcRn / FCGRT&B2M Heterodimer Protein, Strep Tag&Tag Free (MALS & SPR verified)
FCM-H5283-structure
FCM-H5283-sds
FCM-C82W9 Canine Biotinylated Canine FcRn / FCGRT&B2M Heterodimer Protein, His,Avitag™&Tag Free (MALS & SPR verified)
FCM-C82W9-structure
FCM-C82W9-sds
CHEK-ATP079 Human HEK293/Human FcRn (FCGRT & B2M) Stable Cell Line
FCM-C52W8 Canine Canine FcRn / FCGRT&B2M Heterodimer Protein, His Tag&Tag Free (MALS & SPR verified)
FCM-C52W8-structure
FCM-C52W8-sds
FCM-R82W6 Rabbit Biotinylated Rabbit FcRn / FCGRT&B2M Heterodimer Protein, His,Avitag™&Tag Free (MALS&SPR verified)
FCM-R82W6-structure
FCM-R82W6-sds
FCM-R52W5 Rabbit Rabbit FcRn / FCGRT&B2M Heterodimer Protein, His Tag&Tag Free (MALS & SPR verified)
FCM-R52W5-structure
FCM-R52W5-sds
FCM-H82W7 Human Biotinylated Human FcRn / FCGRT&B2M Heterodimer Protein, His,Avitag™ (MALS & SPR verified)
FCM-H82W7-structure
FCM-H82W7-sds
FCM-M52W8 Mouse Mouse FcRn / FCGRT&B2M Heterodimer Protein, His Tag (MALS & BLI verified)
FCM-M52W8-structure
FCM-M52W8-sds
FCM-M82W5 Mouse Biotinylated Mouse FcRn / FCGRT&B2M Heterodimer Protein, His,Avitag™ (MALS & BLI verified)
FCM-M82W5-structure
FCM-M82W5-sds
FCM-C52W9 Cynomolgus / Rhesus macaque Cynomolgus / Rhesus macaque FcRn / FCGRT&B2M Heterodimer Protein, His Tag (MALS & BLI verified)
FCM-C52W9-structure
FCM-C52W9-sds
FCM-C82W3 Cynomolgus / Rhesus macaque Biotinylated Cynomolgus / Rhesus macaque FcRn / FCGRT&B2M Heterodimer Protein, His,Avitag™ (MALS & SPR verified)
FCM-C82W3-structure
FCM-C82W3-sds
FCN-H52W7 Human Human FcRn / FCGRT&B2M Heterodimer Protein, His Tag (SPR & BLI & MALS verified)
FCN-H52W7-structure
FCN-H52W7-sds
FCN-B82W3 Bovine Biotinylated Bovine FcRn / FCGRT&B2M Heterodimer Protein, His,Avitag™ (MALS & SPR verified)
FCN-B82W3-structure
FCN-B82W3-sds
FCN-F82W3 Feline Biotinylated Feline FcRn / FCGRT&B2M Heterodimer Protein, His,Avitag™ (MALS & SPR verified)
FCN-F82W3-structure
FCN-F82W3-sds
FCM-P5280 Porcine Porcine FcRn / FCGRT&B2M Heterodimer Protein, His Tag&Strep II Tag (MALS & SPR verified)
FCM-P5280-structure
FCM-P5280-sds
FCM-C82W5 Cynomolgus / Rhesus macaque Biotinylated Cynomolgus / Rhesus macaque FcRn Heterodimer Protein, His,Avitag™&Strep II Tag (HPLC&SPR&BLI verified)
FCM-C82W5-structure
FCM-C82W5-sds
FCM-C82W5-hplc
FCM-R82W7 Rat Biotinylated Rat FcRn / FCGRT&B2M Heterodimer Protein, Avitag™,His Tag&Strep II Tag (MALS & SPR verified)
FCM-R82W7-structure
FCM-R82W7-sds
FCM-M82W6 Mouse Biotinylated Mouse FcRn / FCGRT&B2M Heterodimer Protein, Avitag™,His Tag&Twin-Strep Tag (MALS & BLI-verified)
FCM-M82W6-structure
FCM-M82W6-sds
FCM-H82W4 Human Biotinylated Human FcRn / FCGRT&B2M Heterodimer Protein, Avitag™,His Tag&Strep II Tag (SPR & BLI & HPLC verified)
FCM-H82W4-structure
FCM-H82W4-sds
FCM-H82W4-hplc
FCM-M52W2 Mouse Mouse FcRn / FCGRT&B2M Heterodimer Protein, His Tag&Twin-Strep Tag (MALS & BLI verified)
FCM-M52W2-structure
FCM-M52W2-sds
FCM-H8286 Human Biotinylated Human FcRn / FCGRT&B2M Heterodimer Protein, His Tag&Strep II Tag, ultra sensitivity (primary amine labeling) (HPLC & SPR verified)
FCM-H8286-structure
FCM-H8286-sds
FCM-H8286-hplc
FCM-R5287 Rat Rat FcRn / FCGRT&B2M Heterodimer Protein, His Tag&Strep II Tag (MALS & SPR verified)
FCM-R5287-structure
FCM-R5287-sds
FCM-C5284 Cynomolgus / Rhesus macaque Cynomolgus / Rhesus macaque FcRn / FCGRT&B2M Heterodimer Protein, His Tag&Strep II Tag (SPR & BLI & MALS verified)
FCM-C5284-structure
FCM-C5284-sds
FCM-H5286 Human Human FcRn / FCGRT&B2M Heterodimer Protein, His Tag&Strep II Tag (SPR & BLI & HPLC-verified)
FCM-H5286-structure
FCM-H5286-sds
FCM-H5286-hplc

일부의 생물활성 데이터

CHEK-ATP132-Cell-based assay
FcRn (FCGRT & B2M) FACS

Fig. FACS analysis of FcRn (FCGRT & B2M) on HEK293/FcRn (FCGRT & B2M), GFP Tag Stable Cell Line.
HEK293/FcRn (FCGRT & B2M), GFP Tag Stable Cell Line was red line, negative control HEK293 cells was grey line(QC tested).

Protocol
CHEK-ATP079-Cell-based assay
FcRn (FCGRT & B2M) FACS

FACS analysis of FcRn (FCGRT & B2M) on HEK293/Human FcRn (FCGRT & B2M) Stable Cell Line.
FACS assay shows that FITC-Labeled Human IgG1 Fc (C103S, M135Y, S137T, T139E, H316K, N317F) Protein, His Tag (Cat. No. IG1-HF2H3) can bind to HEK293/Human FcRn (FCGRT & B2M) Stable Cell Line. HEK293/Human FcRn (FCGRT & B2M) Stable Cell Line was red line, negative control HEK293 cells was grey line(QC tested).

Protocol
FCM-H5283-SPR
FcRn (FCGRT & B2M) SPR

Human IgG1 Fc (C103S, M135Y, S137T, T139E, H316K, N317F), His Tag (Cat. No. IG1-H52H8) immobilized on CM4 Chip can bind Human FCGRT&B2M Heterodimer Protein, Strep Tag&Tag Free (Cat. No. FCM-H5283) with an affinity constant of 23.8 nM as determined in a SPR assay (Biacore 8K) (QC tested).

Protocol
FCM-H5283-SPR
FcRn (FCGRT & B2M) SPR

Herceptin immobilized on CM4 Chip can bind Human FCGRT&B2M Heterodimer Protein, Strep Tag&Tag Free (Cat. No. FCM-H5283) with an affinity constant of 2.67 μM as determined in a SPR assay (Biacore 8K) (Routinely tested).

Protocol

사용자 리뷰

FcRn (FCGRT & B2M) Molecule Synonym Name

FcRn,FCGRT & B2M

FcRn (FCGRT & B2M) Molecule Background

FCGRT & B2M heterodimer protein (FcRn complex) consist of two subunits: p51 (equivalent to FCGRT), and p14 (equivalent to beta-2-microglobulin), and forms an MHC class I-like heterodimer. Fc fragment of IgG, receptor, transporter, alpha (FCGRT) binds to the Fc region of monomeric immunoglobulins gamma and mediates the uptake of IgG from milk. FCGRT possible role in transfer of immunoglobulin G from mother to fetus. Beta-2-microglobulin (B2M) is a component of the class I major histocompatibility complex (MHC) and involved in the presentation of peptide antigens to the immune system.

FcRn (FCGRT & B2M) References

This web search service is supported by Google Inc.

totop
Call us
우리에게 전화하세요
글로벌: +1 800-810-0816 (무료)
아시아태평양: +86 400-682-2521
Email
이메일
order.kr@acrobiosystems.com
Fax
팩스
+1 888-377-6111
Address
주소
서울 성동구 왕십리로10길 6 서울숲비즈포레 703
회사명
아크로바이오 주식회사
사업자 등록번호
186-88-02858
대표자
CHEN YIDING
사업장주소
서울특별시 송파구 중대로12길 10-20, 1층 셀렉티드송파(가락동)
linkedin twitter facebook youtube

문의

Copyright © 2017 ACROBiosystems. All Rights Reserved
Related Links|Privacy Policy|Terms and Conditions|Legal|Sitemap