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Your Position: > C1q R1

C1q R1

요약

Name:Complement component C1q receptor
Target Synonym:C1q/MBL/SPA receptor,C1qR,C1qRp,C1qR(p),CDw93,Complement component 1 q subcomponent receptor 1,Matrix-remodeling-associated protein 4
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:0
Lastest Research Phase:Preclinical

제품 리스트 구매

일부의 생물활성 데이터

C11-H5228-SPR
 C1q R1 SPR

Human IGFBP-7, His Tag (Cat. No. IG7-H5240) immobilized on CM5 Chip can bind Human C1q R1, His Tag (Cat. No. C11-H5228) with an affinity constant of 16.7 μM as determined in a SPR assay (Biacore 8K) (Routinely tested).

C11-H82E9-BLI
 C1q R1 BLI

Loaded Biotinylated Human C1q R1, His,Avitag (Cat. No. C11-H82E9) on SA Biosensor, can bind Human IGFBP-7, His Tag (Cat. No. IG7-H5240) with an affinity constant of 0.93 μM as determined in BLI assay (ForteBio Octet Red96e) (Routinely tested).

Synonym Name

CD93,CDw93,C1QR1,MXRA4,C1qR,C1qR(P),C1qRP,ECSM3

Background

CD antigen CD93 is also known as Complement component C1q receptor (C1QR1). which belongs to the Group XIV C-Type lectin family, a group containing two other members, endosialin (CD248) and thrombomodulin. CD93 contains one C-type lectin domain and five EGF-like domains. CD93 is highly expressed in endothelial cells, platelets, cells of myeloid origin, such as monocytes and neutrophils. CD93 is receptor for C1q, mannose-binding lectin (MBL2) and pulmonary surfactant protein A (SPA). CD93 may mediate the enhancement of phagocytosis in monocytes and macrophages upon interaction with soluble defense collagens and may play a role in intercellular adhesion.

Clinical and Translational Updates

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