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Project Name | Project Stage | Molecule Type | Host Species | Therapeutic Area | Indications |
GPRC5D VHH - 01 | PCC | Hematological Malignancy | Multiple myeloma |
FACS Analysis of CHO/Human GPRC5D Stable Cell Line.
FACS assay shows that Anti-GPRC5D antibody can bind to CHO/Human GPRC5D Stable Cell Line (Fig. B), and non-transfected CHO cells were used as a negative control (Fig. A). PE signal was used to evaluate the binding activity (QC tested).
Anti-GPRC5D Antibody, Human IgG4 captured on Protein A Chip can bind Human GPRC5D Full Length Protein, Flag,His Tag (Cat. No. GPD-H52D5) with an affinity constant of 57.7 nM as determined in a SPR assay (in presence of DDM and CHS) (Biacore 8K) (Routinely tested).
Name | Research Code | Research Phase | Company | Indications | Clinical Trials |
---|---|---|---|---|---|
OriC-321 | OriC-321; Ori-C-321 | Phase 1 Clinical | Zhejiang University | Multiple Myeloma | Details |
MCARH-109 | Phase 1 Clinical | Memorial Sloan Kettering Cancer Center | Multiple Myeloma | Details | |
RO-7425781 | RO-7425781 | Phase 1 Clinical | F. Hoffmann-La Roche Ltd | Multiple Myeloma | Details |
CAR-GPRC5D | CAR-GPRC5D | Phase 1 Clinical | Nanjing Iaso Biotherapeutics Co Ltd | Leukemia, Plasma Cell; Multiple Myeloma | Details |
Autologous anti-BCMA/GPRC5D CAR-T cell therapy (Xuzhou Medical University) | Phase 2 Clinical | Xuzhou Medical University (Xzmu) | Multiple Myeloma | Details | |
Ori-CAR-017 | OriCAR-017; Ori-CAR-017 | Phase 1 Clinical | OriCell Therapeutics Co Ltd | Multiple Myeloma | Details |
Talquetamab | JNJ-7564; JNJ-64407564 | Phase 3 Clinical | Janssen Global Services Llc, Genmab A/S | Hematologic Neoplasms; Multiple Myeloma | Details |
LM-305 | LM-305 | Phase 1 Clinical | LaNova Medicines Ltd | Multiple Myeloma | Details |
RG-6234 | RG-6234 | Phase 1 Clinical | F. Hoffmann-La Roche Ltd | Multiple Myeloma | Details |
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