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Your Position: > Siglec-6

Siglec-6

요약

Name:Sialic acid-binding Ig-like lectin 6
Target Synonym:CD33 antigen-like 1,CDw327,Obesity-binding protein 1 (OB-BP1),OBBP1,CD33L,CD33L1,CD327
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:2
Lastest Research Phase:Phase 2 Clinical

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제품번호 제품 설명 구조 순도 특징
SI6-H5256 Human Human Siglec-6 / CD327 Protein, Fc Tag
SI6-H5256-structure
SI6-H5256-sds

일부의 생물활성 데이터

SI6-H5256-ELISA
 Siglec-6 ELISA

Immobilized Human Siglec-6, Fc Tag (Cat. No. SI6-H5256) at 1 μg/mL (100 μL/well) can bind Monoclonal Anti-Human Siglec-6 Antibody, Rabbit IgG with a linear range of 0.2-16 ng/mL (QC tested).

사용자 리뷰

Synonym Name

SIGLEC6,CD327,CD33L,CD33L1,OBBP1,OB-BP1,CDw327

Background

Sialic acid-binding Ig-like lectin 6 (SIGLEC6) is also known as CD antigen CD327, CD33 antigen-like 1 (CD33L or CD33L1), Obesity-binding protein 1 (OB-BP1). SIGLEC6 belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family, which contains two Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. SIGLEC6 mediates sialic-acid dependent binding to cells. SIGLEC6 binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.

Clinical and Translational Updates

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