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Tau

요약

Name:Microtubule-associated protein tau
Target Synonym:MAPT,MTBT1,Paired helical filament-tau,MAPTL,Microtubule Associated Protein Tau,G Protein Beta1/Gamma2 Subunit-Interacting Factor 1,Protein Phosphatase 1, Regulatory Subunit 103,Neurofibrillary Tangle Protein,PHF-Tau,TAU,Microtubule-Associated Protein Tau, Isoform 4,Microtubule-Associated Protein Tau,PPP1R103,FTDP-17,MTBT2,DDPAC,MSTD,PPND,tau Proteins,MGC138549,FLJ31424
Number of Launched Drugs:1
Number of Drugs in Clinical Trials:34
Lastest Research Phase:Approved

제품 리스트 구매

일부의 생물활성 데이터

CHEK-ATP087-Cell-based assay
 Tau FACS

FACS analysis of Tau-K18 (GFP) on HEK293/Human Tau-K18 (GFP) Stable Cell Line.
HEK293/Human Tau-K18 (GFP) Stable Cell Line was red line, negative control HEK293 cells was grey line (QC tested).

TAU-H5147-ELISA
 Tau ELISA

Immobilized Human Tau-441 GSK-3beta-phosphorylated protein, His Tag (Cat. No. TAU-H5147) at 1 μg/mL (100 μL/well) can bind Anti-Phospho-Tau (Thr181) Monoclonal Antibody, Mouse IgG with a linear range of 1-31 ng/mL (QC tested).

TAU-H5114-MALS-HPLC
Tau MALS images

The purity of Human Tau Protein, Tag Free (Cat. No. TAU-H5114) is more than 90% and the molecular weight of this protein is around 12-20 kDa verified by SEC-MALS.

Synonym Name

DDPAC,FTDP-17,MAPT,MSTD,MTBT1,Tau,PHF-tau,TAU

Background

Tau is a microtubule-associated protein, which encodes by the MAPT gene that located on chromosome 17q21. Tau Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. Hyperphosphorylation of the tau protein (tau inclusions, pTau) can result in the self-assembly of tangles of paired helical filaments and straight filaments, which are involved in the pathogenesis of Alzheimer's disease, frontotemporal dementia, and other tauopathies.

Clinical and Translational Updates

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