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KIR2DL5A

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KIA-H5255 Human Human KIR2DL5 / CD158f Protein, Fc Tag
KIA-H5255-structure
KIA-H5255-sds

일부의 생물활성 데이터

KIA-H5255-ELISA
 KIR2DL5A SPR

Biotinylated Human HLA-G&B2M&Peptide (RIIPRHLQL) Complex Protein (Cat. No. HLM-H82E4) immobilized on CM5 Chip can bind Human KIR2DL5 / CD158f Protein, Fc Tag (Cat. No. KIA-H5255) with an affinity constant of 27.7 μM as determined in a SPR assay (Biacore 8K) (Routinely tested).

Synonym Name

CD158f

Background

Killer cell immunoglobulin-like receptor 2DL5(KIR2DL5), which belongs to the immunoglobulin superfamily, is an inhibitory receptor of NK cells. KIR2DL5 is encoded by two paralogous genes displaying copy number variation and allelic polymorphism-KIR2DL5A and KIR2DL5B that vary by only 2 aa in domain and 1 aa in signal peptide. KIR2DL5 and KIR2DL4 form a subfamily, which have longer cytoplasmic tails than other KIR, and each has one D0 and one D2-type Ig-like domain.

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