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MASP3

요약

Name:Mannan-binding lectin serine protease 1
Target Synonym:Complement-activating component of Ra-reactive factor,Mannose-binding lectin-associated serine protease 1 (MASP-1),Mannose-binding protein-associated serine protease,Ra-reactive factor serine protease p100 (RaRF),Serine protease 5,MASP1,CRARF,PRSS5,Complement factor MASP-3
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:1
Lastest Research Phase:Phase 2 Clinical

제품 리스트 구매

제품 상태별:
제품 유형별 :
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결합물별:
제품번호 제품 설명 구조 순도 특징
MA3-M52H3 Mouse Mouse MASP3 Protein, His Tag (active enzyme, MALS verified)
MA3-M52H3-structure
MA3-M52H3-sds
MA3-H52H3 Human Human MASP3 (450-721) Protein, His Tag (active enzyme)
MA3-H52H3-structure
MA3-H52H3-sds

일부의 생물활성 데이터

The purity of Mouse MASP3 Protein, His Tag (Cat. No. MA3-M52H3) is more than 90% and the molecular weight of this protein is around 30-45 kDa verified by SEC-MALS.

Synonym Name

MASP3, MASP1, CRARF1, RaRF

Background

MASP3 is a member of the MASP family. The MASP family proteins were firstdiscovered as complexes with mannose-binding lectin (MBL) and therefore named MBL-associatedserine proteases, but later, they were found to interact with ficolins, and later still, collectin-10and collectin-11. As well as proteolytic enzymes (MASP-1, MASP-2, MASP-3), the group includesnon-enzymatic factors (MAp19, MAp44). In this review, the association-specific factors of the lectinpathway with haematologic malignancies and related infections are discussed.

Clinical and Translational Updates

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