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IFN-alpha 1

요약

Name:Interferon-alpha/beta receptor alpha chain
Target Synonym:IFNBR,IFN-Alpha-REC,Beta-Type Antiviral Protein,IFNAR,Cytokine Receptor Class-II Member 1,Interferon Receptor 1,IFNAR1,Interferon Alpha/Beta Receptor 1,Interferon Alpha And Beta Receptor Subunit 1,Type I Interferon Receptor 1,Interferon (Alpha, Beta And Omega) Receptor 1,Alpha-Type Antiviral Protein,IFN-Alpha/Beta Receptor 1,AVP,Interferon-Beta Receptor 1,IFRC,IFN-R-1,CRF2-1,Cytokine Receptor Family 2 Member 1,Interferon-Alpha/Beta Receptor Alpha Chain
Number of Launched Drugs:5
Number of Drugs in Clinical Trials:0
Lastest Research Phase:Approved

제품 리스트 구매

일부의 생물활성 데이터

IFA-H5258-BLI
 IFN-alpha 1 BLI

Loaded Human IFN-alpha / beta R1, His Tag (Cat. No. IF1-H5225) on NTA Biosensor, can bind Human IFN-alpha 1, Fc Tag (Cat. No. IFA-H5258) with an affinity constant of 11.3 nM as determined in BLI assay (ForteBio Octet Red96e) (QC tested).

IFA-H5258-BLI
 IFN-alpha 1 BLI

Loaded Human IFNAR2, His Tag (Cat. No. IF2-H5224) on HIS1K Biosensor, can bind Human IFN-alpha 1, Fc Tag (Cat. No. IFA-H5258) with an affinity constant of 2.67 nM as determined in BLI assay (ForteBio Octet Red96e) (Routinely tested).

사용자 리뷰

Synonym Name

IFN-alpha 1,IFNA1,IFNalpha 1,IFN-alpha-1,LeIF D

Background

Interferon alpha-1 is also known as IFN-alpha-1/13, Interferon alpha-D, LeIF D and IFNA1, belongs to the alpha / beta interferon family. Interferons alpha-1 and alpha-13 have identical protein sequences. Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. IFN-alpha can either suppress or promote the development of autoimmune diabetes. It is likely that IFN-alpha plays a complex role in the etiology of type 1 diabetes.

Clinical and Translational Updates

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