Introduction
As an essential tool in biopharmaceutical research and development, functional cell lines offer stability, broad applicability, and rich biological characteristics, making them extensively used in target validation, mechanism exploration, high-throughput drug screening, analytical testing, quality control (QC) release, as well as pharmacodynamics and toxicology studies.
In the biopharmaceutical development process, obtaining commercial licensing for functional cell line products is a critical prerequisite to ensure the legal and compliant advancement of projects. This process not only safeguards intellectual property rights but also facilitates the smooth progression of research and development activities within the regulatory framework.
ACROBiosystems has officially secured global commercial usage rights for HEK293, CHO, Jurkat, Raji cell lines, enabling it to provide comprehensive licensing support and services worldwide. This strategic achievement significantly enhances ACROBiosystems' portfolio of functional cell line products and services, offering biopharmaceutical developers and CRO/CDMO partners robust regulatory and intellectual property assurance. By offering this critical support, ACROBiosystems empowers its partners across the entire drug development process—from early-stage research and regulatory submissions to successful commercialization — ensuring a seamless and compliant pathway for innovation and market entry.
Core Value
ACROBiosystems' functional cell line license support service is designed to assist biopharmaceutical developers and CRO/CDMO partners in obtaining commercial licenses for cell line products in a legally compliant manner. From the outset of a project, this service helps customers mitigate intellectual property and compliance risks, ensuring the use of properly authorized cell lines. By preventing the utilization of unclear or unauthorized cell lines, it safeguards against potential disruptions to commercialization and technology transfer, which could otherwise result in significant financial and operational setbacks. Moreover, this service contributes to accelerating drug development timelines and reducing associated costs, enabling partners to focus on innovation and expediting the journey from research to market.
• Clear Cell Line Origin: ACRO’s cell line products are sourced from globally recognized and authoritative cell banks, ensuring clear and traceable origins. Comprehensive documentation is available to support global regulatory filings and project transfers, enabling customers to meet compliance requirements with confidence.
• Well-Defined Intellectual Property (IP) Rights: ACRO’s cell lines are formally licensed from original rights holders, granting ACRO the authority to modify, develop, and commercialize related products. The modified cell lines have clear IP ownership, and ACRO holds the rights to further authorize these cell lines. Customers using ACRO’s cell lines for drug development, regulatory submissions, or project transfers can eliminate future IP-related risks, ensuring a secure and compliant pathway for their projects.
• Global Commercial Authorization Support: ACRO’s dedicated international IP and legal team provides end-to-end support to help customers secure global commercial usage rights for cell line products. This ensures smooth regulatory compliance worldwide, enabling customers to navigate complex legal landscapes and accelerate their drug development processes with peace of mind.
License Scope
| Cell Type | Description | Rights Officially Secured by ACRO |
|---|
| HEK 293 | Derived from human embryonic kidney cells, this cell line exhibits strong transfection capability and efficiently expresses exogenous genes. It is commonly used for therapeutic antibody production, engineered antibody screening, and optimization | 1. Commercial usage rights for the cell line
2. Rights to modify, derive, and develop the cell line, as well as global sales rights for cell line products
3. Global support for commercial license and usage |
| CHO | Derived from Chinese hamster ovary (CHO) cells, this cell line exhibits high-efficiency protein expression and is widely used for therapeutic protein and antibody production |
| Jurkat | Derived from the peripheral blood of a human acute T-cell leukemia patient, this cell line is highly sensitive to TCR signaling and is commonly used in tumor immunotherapy research and antibody efficacy studies |
| Raji | Derived from human Burkitt lymphoma cells, this cell line expresses B-cell surface antigens and is commonly used in drug research for cancer treatment |
ACROBiosystems’s Functional Cell Line Products
To address the evolving demands of new drug development, ACROBiosystems, leveraging its featured cell line development platform and extensive expertise in drug analysis assays and application technologies, has successfully developed over a hundred functional cell line, using HEK293, CHO, Jurkat, and Raji as host cells. Additionally, our functional cell line team offers a worry-free, one-stop custom cell line development service, tailored to meet your specific requirements. This comprehensive offering ensures that our partners receive precisely engineered cell lines, empowering their research and development efforts with unparalleled precision and efficiency.
Product Advantages
Genetically modified cell lines best reflect MOA (Mechanism of Action)
Higher activity and larger assay window for robust and reproducible cell-based bioassay
Comprehensive application data to support assay development and validation
Full tracible record, stringent quality control and validated cell passage stability
Parental cell lines legally obtained from internationally recognized cell resource banks and commercially licensed
Global commercial license assistance whenever regulatory filing is required
Limited Edition Golden Llama is here! Check out how you can get one. 
Limited Edition Golden Llama is here! Check out how you can get one. 
A-Z
